Survivorship Issues in Testicular Cancer

Authors

  • Marco Pisino, MD Division of Medical Oncology, Vito Fazzi Hospital, Lecce, Italy
  • Lucia Nappi, MD Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada British Columbia Cancer – Vancouver Centre, Department of Medicine – Division of Medical Oncology, University of British Columbia, Vancouver, BC, Canada

DOI:

https://doi.org/10.58931/cot.2024.1223

Abstract

Testicular cancer (TC) is the most prevalent tumor in young men aged 15–40 years, with an annual incidence of 3–11 new cases per 100,000 males in Western countries. In 2020, the International Agency for Research on Cancer reported 74,458 newly diagnosed cases of TC globally. The etiology of TC is complex and includes both genetic and environmental factors. The prognosis of TC is excellent with a >90% cure rate and a >95% 5-year survival rate with appropriate treatment. Treatments for TC include active surveillance, chemotherapy, radiotherapy, and retroperitoneal lymph node dissection, depending on the clinical stage and tumor subtype. It is crucial that patients receive information on the diagnosis, therapeutic management options, consequences of treatments, and surveillance protocols, which allows the patient to play an active role in the decision-making process. Fear of recurrence often affects TC survivors. Therefore, it is essential to fully involve the patient in the choice of the treatment to ensure an optimal compliance, especially when selecting the active surveillance strategy. In the modern era, in light of the excellent outcomes achieved in TC management, one of the high priorities is to deliver curative treatments while minimizing long-term toxicity. This focus can have a positive impact on quality of life and life expectancy of TC survivors. 

Author Biographies

Marco Pisino, MD, Division of Medical Oncology, Vito Fazzi Hospital, Lecce, Italy

Dr. Pisino is a medical oncologist at the “Vito Fazzi” Hospital in Lecce, Italy, with a clinical practice specializing in genitourinary malignancies. He completed his medical degree and training at the University of Parma, followed by an oncology residency at the University of Bari. Most recently, he pursued a fellowship in Genitourinary Oncology through the Italian Foundation “La Clessidra” at the University of British Columbia under Dr. Lucia Nappi’s supervision, with a research focus on testicular cancer. 

Lucia Nappi, MD, Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada British Columbia Cancer – Vancouver Centre, Department of Medicine – Division of Medical Oncology, University of British Columbia, Vancouver, BC, Canada

Dr. Lucia Nappi is a medical oncologist - clinician scientist, MD and PhD. She is an assistant professor in the department of Urologic Sciences at the University of British Columbia and a senior research scientist at the Vancouver Prostate and works as medical oncologist in the GU group at the BC Cancer in Vancouver. Her main research focus involves the discovery and validation of biomarkers in GU cancers, mainly in prostate and testis cancer patients. She has got several grants and awards including the Prostate Cancer Foundation Young Investigator award and the Michael Smith Foundation Health Professional Investigator award (2020), the operational CIHR grant in 2021, the R37 NIH grant and the career development award from the US department of defense (2022). She is the vice-chair of the SWOG Adolescent and Young Adults (AYA) committee and the chair of the international SWOG-S1823/CCTG GCC.1 clinical trial. 

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Published

2024-06-20

How to Cite

Pisino, M., & Nappi, L. (2024). Survivorship Issues in Testicular Cancer. Canadian Oncology Today, 1(2), 28–36. https://doi.org/10.58931/cot.2024.1223

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